RETA
Price range: $100.00 through $210.00
Product on sale
Reta
Reta Research Grade (RUO) (CAS 2381089-83-2, LY3437943) is a 39–amino acid unimolecular peptide designed as a triple agonist for GIP / GLP-1 / Glucagon (GCG) receptors. Supplied as a lyophilized white powder with ≥99% purity (HPLC verified) and endotoxin <1.0 EU/mg, it is soluble in sterile or bacteriostatic water.
The molecule includes a C20 fatty diacid moiety for albumin binding and extended stability (reported ~6-day half-life), supporting metabolic, obesity, T2D, and hepatic defatting research models.
For Research Use Only (RUO). Not for human or veterinary use.
Product Specifications
- Product Name : Reta (Research Grade)
- CAS Number : 2381089-83-2
- Common Name : LY3437943
- Molecular Formula : C221H342N46O68
- Molecular Weight : 4731 g/mol
- Peptide Type : Triple-Hormone Receptor Agonist
- Target Receptors : GIP / GLP-1 / Glucagon (GCG)
- Purity : ≥99% (HPLC Verified)
- Form : Lyophilized White Powder
- Solubility : Soluble in sterile water or bacteriostatic water
- Endotoxin Level : Less than 1.0 EU/mg
Disclaimer : For Research Use Only (RUO). Not for human use.
Chemical Identity & Structural Mechanism
Reta is a synthetic unimolecular peptide comprising 39 amino acids. Unlike dual agonists, it integrates activity at the Glucagon Receptor (GCGR) alongside GIP and GLP-1, creating a “Triple Synergy”.
Structure-Activity Relationship (SAR): The backbone is derived from GIP but modified to introduce Glucagon activity. It features a C20 fatty diacid moiety that binds to albumin, protecting the peptide from enzymatic degradation and extending its half-life to approximately 6 days.
Tuned Potency: Reta is designed with a specific hierarchy of potency: highest at GIP (for lipid buffering), moderate at GLP-1 (for satiety), and carefully tuned at Glucagon (to drive energy expenditure without hyperglycemia) .
DISCLAIMER:
- Products sold on our website are meant for scientific research purposes only, designed for in vitro testing and lab experimentation exclusively. These products are not intended to be used as foods, drugs or cosmetics, any sort of bodily introduction of the products into humans or animals is strictly prohibited.
- All the products you see on the website are being sold as a freeze dried powder, in a sealed sterile vial; and should be reconstituted.
The product’s label clearly states the amount of product a vial contains; some products are offered in different variations. - The products we are selling come in a sealed vial but require additional lab equipment for proper testing.
- Though we make sure packaging, label, seals and writing does not differ from the product photos you see on our website, there is a chance for a minimal deviation.
| Attributes | Value |
|---|---|
| Dosage |
10 mg, 20 mg, 30 mg |
